The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells.
Pathway
B Cell Receptor Signaling Pathway; Direct p53 effectors; FoxO family signaling; IL4-mediated signaling events; Signaling events mediated by HDAC Class II; Transcriptional misregulation in cancers; Transcriptional misregulation in cancers
Citations
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