Anti-APOC3 (native protein) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Syrian Hamster

Immunogen

Full length native apoLipoprotein Type C-III (purified).

Conjugate

Application Notes

ELISA: 1/5000 - 1/10000; IHC-P: 1/50 - 1/200; WB: 1/500 - 1/5000; IP 1/100.

Alternative Names

APOC3; apolipoprotein C-III; APO C3; Apo CIII; APoC 3; ApoC III; APOC3; ApoCIII; Apolipoprotein C III; ApolipoproteinCIII; MGC150353; apo-CIII; apoC-III; apolipoprotein C3; HALP2; APOCIII;

Entrez Gene ID

UniProt ID

Antigen Description

Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein.APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles.The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes.The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed.An increase in apoC-III levels induces the development of hypertriglyceridemia.

Pathway

Chylomicron-mediated lipid transport, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem; Statin Pathway, organism-specific biosystem;