Specifications
Immunogen
A synthetic peptide of human HTR3B is used for rabbit immunization.
Target
Alternative Names
HTR3B; 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic; 5 hydroxytryptamine (serotonin) receptor 3B; 5-hydroxytryptamine receptor 3B; 5 HT3B; 5-HT3-B; serotonin-gated ion channel subunit; 5-hydroxytryptamine 3 receptor B subunit; 5-HT3B;
Product Background
Antigen Description
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude.
Pathway
Ion channel transport, organism-specific biosystem; Ligand-gated ion channel transport, organism-specific biosystem; Serotonergic synapse, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem.
Citations
Publication ()
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COA
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