Anti-HSV type 2 Polyclonal antibody

The diagnosis of herpes simplex virus (HSV) genital infection is primarily clinical. The primary indication for serodiagnosis is to detect seronegativity in pregnant women at risk of acquiring the HSV virus during the course of their pregnancy. In this study, two ELISA tests were compared for the detection of HSV infection among a population of 307 pregnant women followed at the maternity of a community-based hospital in France (Robert Ballanger hospital in the Seine-Saint-Denis department). The two tests compared were: Test Captia T anti-HSV-1 and anti-HSV-2 specifics IgG of Trinity Biotech and the ELISA IgG HerpesSelect r 1 and 2 of FOCUS Diagnostics distributed by Eurobio Courtaboeuf, France. Results: both tests results were similar in terms of population prevalence for HSV-1 and HSV-2 infections (respectively 86.64% and 85.99% for HSV-1; 17.59% and 15.31% for HSV2). Whereas the prevalence of the HSV-1 virus was described in the literature as being superior to our current results, the prevalence of HSV-2 according to the results of both ELISA tests studied was similar to the one described in previous cohort studies.

a survey to identify the aetiology of hearing impairment among Saudi children was carried out, Children were divided into two groups according to presence or absence of laboratory evidence of herpes simplex virus infection 'at risk' and 'not at risk', Serological tests for herpes simplex virus infection mere performed on 1054 children, We found positive IgM antibody against herpes simplex virus, type I (HSV1) in the blood of 82 of the 1054 children (8 per cent), and positive lgM antibody against herpes simplex virus type 2 (HSV2) in eight of the 1054 children (0.8 per cent) ages ranged between 12 months and 14 years), Forry-six of the eighty-two infected children (56 per cent) with HSV1 mere found to have bilateral sensorineural hearing loss (16 of 26 children of the at risk group and 30 of 54 from the 'not at risk' group), Only one case of the eight infected children with HSV2 was found to have bilateral sensorineural hearing loss of moderate degree. This case was in the 'not at risk' group, Hearing impairment was bilateral in all 46 cases, profound in seven, moderate to severe in 23 and mild int 16, Known causes of hearing impairment mere excluded together with hearing impairment due to multiple TORCH agents, The high prevalence of hearing impairment among children due to herpes simplex virus infection is described.