Mouse Anti-Human HSP90B1 Monoclonal Antibody (DPABH-01087)
Mouse Anti-Human HSP90B1 Monoclonal Antibody for IHC, WB, ICC-IF
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Recombinant Protein, antigen sequence: SGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTA
ICC-IF: 1-4 µg/ml
IHC: 1:500 - 1:1000
WB: 1 µg/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Immunohistochemical staining of human prostate shows strong cytoplasmic immunoreactivity in glandular cells.
Immunofluorescence staining in HeLa cell line with Anti-HSP90B1 monoclonal antibody, showing specific staining of endoplasmic reticulum in green. Microtubule- and nuclear probes are visualized in red and blue respectively (where available). Antibody staining is shown in green.
HSP90B1; heat shock protein 90kDa beta (Grp94), member 1; ECGP; GP96; TRA1; GRP94
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Liu, B; Li, ZH; et al. Endoplasmic reticulum HSP90b1 (gp96, grp94) optimizes B-cell function via chaperoning integrin and TLR but not immunoglobulin. BLOOD 112:1223-1230(2008).
Rosenbaum, M; Andreani, V; et al. MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress. GENES & DEVELOPMENT 28:1165-1178(2014).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.