Anti-HSD17B10 monoclonal antibody, clone FQS22949(C)

Name: Anti-HSD17B10 monoclonal antibody, clone FQS22949(C)
SKU: DCABH-5440

Rabbit anti-Human HSD17B10 monoclonal antibody for WB, IHC-P

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Clone

FQS22949(C)

Species Reactivity

Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human ERAB.Database link: Q99714

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100;

Target

Alternative Names

HSD17B10; hydroxysteroid (17-beta) dehydrogenase 10; HADH2, hydroxyacyl Coenzyme A dehydrogenase, type II, hydroxyacyl Coenzyme A dehydrogenase, type II , mental retardation, X linked, syndromic 10 , MRXS10; 3-hydroxyacyl-CoA dehydrogenase type-2; 17b H

Entrez Gene ID

3028

UniProt ID

Q99714

Product Background

Antigen Description

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

Pathway

Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Branched-chain amino acid catabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Tryptophan metabolism, organism-specific biosystem;

Citations