Specifications
Immunogen
Synthetic peptide corresponding to a region within Human HSD11B1 (P28845).
Applications
Application Notes
WB: 1/10000 - 1/50000; IHC-P: 1/50 - 1/100; ICC/IF: 1/50 - 1/100;
Target
Alternative Names
HSD11B1; hydroxysteroid (11-beta) dehydrogenase 1; HSD11, HSD11B; corticosteroid 11-beta-dehydrogenase isozyme 1; SDR26C1; short chain dehydrogenase/reductase family 26C; member 1; short chain dehydrogenase/reductase family 26C, member 1; HDL; 11-DH; HSD1
Product Background
Antigen Description
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol.
Pathway
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone, organism-specific biosystem; cortisol/cortisone, conserved biosystem; Glucocorticoid & amp; Mineralcorticoid Metabolism, organism-specific biosystem.
Citations
Publication ()
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COA
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