Anti-HIV RT Monoclonal antibody (DMAB8405)

Mouse Anti-HIV RT Monoclonal antibody for ELISA, AP, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
BT35
Species Reactivity
HIV
Immunogen
Recombinant immuno-deficiency virus reverse transcriptase (HIV-RT).
Conjugate
Unconjugated

Target


Alternative Names
Group VI (ssRNA-RT); Retroviridae; Lentivirus; Human immunodeficiency virus 1; Human immunodeficiency virus 2; HIV 1 Reverse transcriptase

Product Background


Antigen Description
HIV1 Reverse Transcriptase is an RNA-dependent DNA polymerase of HIV1 (AIDS virus), subtype B origin. It is responsible for the production of a double stranded DNA copy of the single stranded RNA genome that is contained in the HIV1 virus particle and primed by the host cell lysine-tRNA which partly unfolds and anneals to the 5" end of the viral genomic RNA. This is extended by the polymerase function of RT to give a DNA-RNA hybrid. It also has RNaseH activity which degrades the RNA component of this hybrid once it has been copied.

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