Anti-HIST2H2AA3 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human HIST2H2AA3 is used for rabbit immunization.

Conjugate

Alternative Names

HIST2H2AA3; histone cluster 2, H2aa3; H2A histone family, member O , H2AFO, HIST2H2AA, histone 2, H2aa , histone 2, H2aa3; histone H2A type 2-A; H2A.2; H2A/q; histone H2A.2; histone H2A/o; histone 2, H2aa3; H2A histone family, member O; H2A; H2A/O; H2AFO;

Entrez Gene ID

UniProt ID

Antigen Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Pathway

Amyloids, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; Disease, organism-specific biosystem; Gene Expression, organism-specific biosystem; Meiosis, organism-specific biosystem.