This gene encodes a conserved homeobox protein that is a transcriptional repressor in the developing forebrain and pituitary gland. Mutations in this gene are associated with septooptic dysplasia, HESX1-related growth hormone deficiency, and combined pituitary hormone deficiency.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Dattani, MT; et al. Growth hormone deficiency and combined pituitary hormone deficiency: does the genotype matter?. CLINICAL ENDOCRINOLOGY 63:121-130(2005).
Reynaud, R; Albarel, F; et al. Pituitary stalk interruption syndrome in 83 patients: novel HESX1 mutation and severe hormonal prognosis in malformative forms. EUROPEAN JOURNAL OF ENDOCRINOLOGY 164:457-465(2011).
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Certificate of Analysis