Anti-GCG monoclonal antibody (DMAB3415MH)

Mouse anti-Human GCG monoclonal antibody for ICC, Dot, IHC(PFA fixed) Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
JD/GLP-3/20
Species Reactivity
Human
Immunogen
Synthetic human Glucagon Like Peptide 1 (GLP1) peptide KLH conjugated, amino acid sequence 7-36 amide
Conjugate
Unconjugated

Target


Alternative Names
GCG; Gcg; GLP 1; GLP 2; GLP2; glucagon
Entrez Gene ID
UniProt ID

Product Background


Pathway
Class B/2 (Secretin family receptors); FOXA1 transcription factor network; G alpha (s) signalling events; Glucagon-type ligand receptors; Integration of energy metabolism

Citations


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References


Nguyen, KH; Yao, XH; et al. Human IGF Binding Protein-3 Overexpression Impairs Glucose Regulation in Mice via an Inhibition of Insulin Secretion. ENDOCRINOLOGY 152:2184-2196(2011).
Jimenez-Solem, E; Rasmussen, MH; et al. Dulaglutide, a long-acting GLP-1 analog fused with an Fc antibody fragment for the potential treatment of type 2 diabetes. CURRENT OPINION IN MOLECULAR THERAPEUTICS 12:790-797(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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