Intended Use
The assay is intended for the quantitative determination of anti-gliadin-sIgA antibodies in stool. For in vitro diagnostic use only.
Contents of Kit
1. One holder with precoated strips, 12 x 8 wells
2. ELISA wash buffer concentrate 10x, 2 x 100 mL
3. Conjugate (Peroxidase-labeled), 1 x 15 mL
4. Control negative, lyophilized, 4 vials
5. Control positive, lyophilized, 4 vials
6. Cut-off Control, lyophilized, 4 vials
7. TMB substrate (Tetramethylbenzidine), 1 x 15 mL
8. ELISA stop solution, 1 x 15 mL
9. Extraction buffer concentrate, 2.5x, 1 x 100 mL
Storage
The reagents are stable up to the expiry date stated on the label when stored at 2-9°C. For more detailed information, please download the following document on our website.
General Description
The celiac/coeliac disease is caused by the gliadin fraction of wheat gluten and similar proteins of rye and barley. The disease is manly manifested as chronic digestion insufficiency in children or young adults. In addition, patients with celiac disease have a greatly increased risk of developing malignant T-cell lymphoma of the small bowel, as T-cell lymphoma was found in 6 of 10 patients with coeliac sprue. Early diagnosis of celiac disease is important, because there is evidence that a gluten-free diet might help to prevent complications and malignancies (including intestinal lymphoma).
The measurement of anti-gliadin-sIgA-antibodies may be useful as a screening criterion before jejunal biopsy, the "Gold Standard", and for the monitoring of the gluten-free diet treatment.
Indication:
1. Celiac disease
2. Food intolerance
Datasheet