Specifications
Species Reactivity
Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100; ICC: 1/50 - 1/100;
Target
Alternative Names
GTF2E1; general transcription factor IIE, polypeptide 1 (alpha subunit); general transcription factor IIE, polypeptide 1, alpha;
Product Background
Antigen Description
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Pathway
Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Gene Expression, organism-specific biosystem; RNA Polymerase II Pre-transcription Events, organism-specific biosystem; RNA Polymerase II Promoter Escape, organism-specific biosystem; RNA Polymerase II Transcription, organism-specific biosystem;
Citations
Publication ()
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COA
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