Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Moslehi, R; Ambroggio, X; et al. Nucleotide excision repair/transcription gene defects in the fetus and impaired TFIIH-mediated function in transcription in placenta leading to preeclampsia. BMC GENOMICS 15:-(2014).
PIRAS, G; KASHANCHI, F; et al. TRANSCRIPTION OF THE HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE-I PROMOTER BY AN ALPHA-AMANITIN-RESISTANT POLYMERASE. JOURNAL OF VIROLOGY 68:6170-6179(1994).
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