Anti-GRIN1 monoclonal antibody (DCABH-6029)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
7C22
Species Reactivity
Mouse, Human
Immunogen
Recombinant fragment within Human NMDAR1 C1 (N terminal). The exact sequence is proprietary. With Proprietary tag.Database link: Q05586
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/3000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
GRIN1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; NMDAR1; glutamate [NMDA] receptor subunit zeta-1; GluN1; NMD-R1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Masuho, I; Mototani, Y; et al. Dynamic expression patterns of G protein-regulated inducer of neurite outgrowth 1 (GRIN1) and its colocalization with G alpha o implicate significant roles of G alpha o-GRIN1 signaling in nervous system. DEVELOPMENTAL DYNAMICS 237:2415-2429(2008).
Demontis, D; Nyegaard, M; et al. Association of GRIN1 and GRIN2A-D With Schizophrenia and Genetic Interaction With Maternal Herpes Simplex Virus-2 Infection Affecting Disease Risk. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 156B:913-922(2011).

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