Anti-GPSM1 (aa 450-500) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide within Human GPSM1 aa 450-500. The exact sequence is proprietary. (NP_001139110.1)Database link: Q86YR5

Conjugate

Application Notes

IP: 2-10 μg/mg

Alternative Names

GPSM1; G-protein signaling modulator 1; G protein signalling modulator 1 (AGS3 like, C. elegans); G-protein-signaling modulator 1; AGS3; AGS3 homolog (C. elegans); DKFZP727I051; AGS3 homolog; activator of G-protein signaling 3; G-protein signalling modula

Entrez Gene ID

UniProt ID

Antigen Description

Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.

Pathway

Cocaine addiction;