The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Mach, N; Gao, Y; et al. The peripheral blood transcriptome reflects variations in immunity traits in swine: towards the identification of biomarkers. BMC GENOMICS 14:-(2013).
Tewary, P; Yang, D; et al. Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin. BLOOD 116:3465-3474(2010).
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COA
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