The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.
Pathway
ADP signalling through P2Y purinoceptor 12; Adenylate cyclase inhibitory pathway; Adrenergic signaling in cardiomyocytes; Alcoholism
Citations
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