Rabbit Anti-Human GMIP (a.a. 1-91) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human GMIP protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-91 aa of BC126436

Conjugate

Application Notes

WB: 1:1000-1:4000
IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate
IHC: 1:50-1:500

General Notes

This product (Catalog No. DPABH-25531) is a rabbit-derived polyclonal antibody raised against human GMIP, targeting the amino acid region 1–91 of the protein. It has been affinity purified by Protein A. GMIP (Gem-interacting protein) is a 970 amino acid protein that stimulates the GTPase activity of RhoA in vitro and in vivo. GMIP interacts with Gem through its N-terminus and has a Rho GTPase-activating protein domain at its C-terminus. The Rho family of GTP-binding proteins plays a role in the development of neuronal structure. GMIP is able to inhibit RhoA function, leading to Actin cytoskeletal reorganization in vivo.
DPABH-25531 is suitable for use in Western blot (WB) (1:1,000–1:4,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:50–1:500) applications.
DPABH-25531 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ARHGAP46; GEM interacting protein; GEM-interacting protein

Entrez Gene ID

UniProt ID