Rabbit Anti-Human GLRB (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human GLRB.

Conjugate

Application Notes

WB: 1:500-1:3000

General Notes

This product (Catalog No. DPABH-21746) is a rabbit-derived IgG polyclonal antibody raised against human GLRB. It has been affinity purified by protein A. This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
DPABH-21746 is suitable for use in Western blot (WB) (1:500–1:3,000) application.
DPABH-21746 is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Glycine receptor subunit beta; Glycine receptor 58 kDa subunit

Entrez Gene ID

UniProt ID