Antibody was raised against an 18 amino acid peptide near the center of human GLIPR1.
Conjugate
Unconjugated
Target
Alternative Names
GLIPR1; GLI pathogenesis-related 1; GLIPR; RTVP1; CRISP7; glioma pathogenesis-related protein 1; gliPR 1; protein RTVP-1; GLI pathogenesis-related 1 (glioma); testes-specific vespid and pathogenesis protein 1; related to testis-specific, vespid, and patho
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Pathway
Fatty acid; Metabolism; Metabolism of lipids and lipoproteins; PPARA activates gene expression; Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Citations
Publication ()
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