Anti-GCKR monoclonal antibody (DCABH-749)

Mouse anti-Human GCKR monoclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
0H8
Species Reactivity
Human
Immunogen
Recombinant full length Human GCKR produced in HEK293T cells (NP_001417).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
GCKR; glucokinase (hexokinase 4) regulator; glucokinase (hexokinase 4) regulatory protein; glucokinase regulatory protein; GKRP; FGQTL5
Entrez Gene ID
UniProt ID

Product Background


Pathway
Glucose transport, organism-specific biosystem; Hexose transport, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; Regulation of Glucokinase by Glucokinase Regulatory Protein, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem;

Citations


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References


Rees, MG; Ng, D; et al. Correlation of rare coding variants in the gene encoding human glucokinase regulatory protein with phenotypic, cellular, and kinetic outcomes. JOURNAL OF CLINICAL INVESTIGATION 122:205-217(2012).
Weissglas-Volkov, D; Aguilar-Salinas, CA; et al. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. JOURNAL OF MEDICAL GENETICS 50:298-308(2013).

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