Anti-GCGR polyclonal antibody (DPABH-25666)
Rabbit Anti-Human GCGR (aa 300-400) polyclonal antibody for WB
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Synthetic peptide conjugated to KLH derived from within residues 300 - 400 of Human Glucagon Receptor.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
GCGR; glucagon receptor; GGR; GL-R
Class B/2 (Secretin family receptors); G alpha (s) signalling events; GPCR ligand binding; Gastrin-CREB signalling pathway via PKC and MAPK
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Sloop, KW; Michael, MD; et al. Role of the glucagon receptor in glucose homeostasis: a therapeutic target to improve glycemic control in type 2 diabetes. DRUGS OF THE FUTURE 29:835-841(2004).
Gu, W; Lloyd, DJ; et al. Pharmacological Targeting of Glucagon and Glucagon-Like Peptide 1 Receptors Has Different Effects on Energy State and Glucose Homeostasis in Diet-Induced Obese Mice. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 338:70-81(2011).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.