Anti-GCGR polyclonal antibody (DPABH-25666)
Rabbit Anti-Human GCGR (aa 300-400) polyclonal antibody for WB
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Synthetic peptide conjugated to KLH derived from within residues 300 - 400 of Human Glucagon Receptor.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
GCGR; glucagon receptor; GGR; GL-R
Class B/2 (Secretin family receptors); G alpha (s) signalling events; GPCR ligand binding; Gastrin-CREB signalling pathway via PKC and MAPK
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Lau, YY; Ma, PM; et al. Pharmacokinetic and Pharmacodynamic Modeling of a Monoclonal Antibody Antagonist of Glucagon Receptor in Male ob/ob Mice. AAPS JOURNAL 11:700-709(2009).
Yan, H; Gu, W; et al. Fully Human Monoclonal Antibodies Antagonizing the Glucagon Receptor Improve Glucose Homeostasis in Mice and Monkeys. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 329:102-111(2009).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.