Transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells.
Pathway
C-MYB transcription factor network; Factors involved in megakaryocyte development and platelet production; Hemostasis; IL-3 Signaling Pathway; Notch-mediated HES/HEY network; Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Cla
Citations
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