Gamma-aminobutyric acid A receptors [GABA(A) receptors]are ligand-gated chloride channels that mediate inhibitoryneurotransmission. This gene encodes GABA(A) receptor-associatedprotein, which is highly positively charged in its N-terminus andshares sequence similarity with light chain-3 ofmicrotubule-associated proteins 1A and 1B. This protein clustersneurotransmitter receptors by mediating interaction with thecytoskeleton.
Pathway
FoxO signaling pathway; GABAergic synapse; Regulation of autophagy; Senescence and Autophagy
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