Magic™ Anti-BNP monoclonal antibody (DCAB-TJ192)

Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
BC-COQ3
Species Reactivity
Human
Immunogen
Immune complex formed by Fab-fragment of BNP-specific DMAB1755MH. and synthetic human BNP.
Conjugate
Unconjugated

Applications


Application Notes
EIA, ELISA(Det)
We recommend the following for sandwich ELISA (Capture - Detection):
DMAB1755MH - DCAB-TJ192
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
Fab24C5-BNP; Brain natriuretic peptide; BNP

Product Background


Antigen Description
Brain natriuretic peptide (BNP), now known as B-type natriuretic peptide or Ventricular Natriuretic Peptide (still BNP), is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). The release of BNP is modulated by calcium ions. BNP is named as such because it was originally identified in extracts of porcine brain, although in humans it is produced mainly in the cardiac ventricles. Suitable for use in ELISA as a detection antibody only when used with Catalog #DMAB1755MH as the capture antibody. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but
Suggested pair for testing (Capture - Detection): DMAB1755MH - DCAB-TJ192.

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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Hom, NM; Promptmas, C; et al. Detection of DNA Hybridization Using Protein A Modified Ion Sensitive Field Effect Transistor. ANALYTICAL LETTERS 48:1128-1138(2015).
Ruixo, JJP; Doshi, S; et al. Quantitative Pharmacology of Denosumab in Patients with Bone Metastases from Solid Tumors. JOURNAL OF CLINICAL PHARMACOLOGY 55:S85-S92(2015).

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