Anti-FRMD6 polyclonal antibody (DPABH-00408)

Rabbit anti-Human FRMD6 (C-terminal) polyclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to Human FRMD6 aa 600 to the C-terminus conjugated to Keyhole Limpet Haemocyanin (KLH).Database link: Q96NE9
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 μg/ml; ICC/IF: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
FRMD6; FERM domain containing 6; EX1; Willin; C14orf31; c14_5320
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
FRMD6 (FERM domain containing 6) is a protein-coding gene. Diseases associated with FRMD6 include alzheimers disease , and squamous cell carcinoma. An important paralog of this gene is FRMD1. FERM domain-containing protein 6 is a protein that in humans is encoded by the FRMD6 gene.
Pathway
Hippo signaling pathway.

Citations


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References


Barsukov, IL; Prescot, A; et al. Phosphatidylinositol phosphate kinase type 1 gamma and beta(1)-Integrin cytoplasmic domain bind to the same region in the talin FERM domain. JOURNAL OF BIOLOGICAL CHEMISTRY 278:31202-31209(2003).
Hamada, K; Shimizu, T; et al. Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of the adhesion protein ICAM-2. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 57:891-892(2001).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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