Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
Pathway
Terpenoid backbone biosynthesis;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Kurth, DD; Farh, L; et al. Functional consequence of mutating conserved residues of the yeast farnesyl-protein transferase beta-subunit Ram1(Dpr1). BIOCHEMISTRY 36:15932-15939(1997).
Huang, CF; Chen, CH; et al. Disrupting the transforming activity of shrimp ras(Q(61)K) by deleting the CAAX box at the C-terminus. JOURNAL OF EXPERIMENTAL ZOOLOGY 289:441-448(2001).
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