CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. Clone LE2 recognizes both forms of CD16 and will therefore recognize all cell types expressing CD16.
Pathway
Adaptive Immune System; Allograft rejection; Antigen processing and presentation; Asthma; Autoimmune thyroid disease; Cell adhesion molecules (CAMs); Costimulation by the CD28 family; Cytokines and Inflammatory Response (BioCarta); Downstream TCR signaling; Generation of second messenger molecules; Graft-versus-host disease; HTLV-I infection; Herpes simplex infection; Immune System; Inflammatory bowel disease (IBD); Influenza A; Intestinal immune network for IgA production; Leishmaniasis; MHC cl
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