Anti-FABP2 monoclonal antibody, clone 0B0C8C4

Antibody Isotype

IgG1

Clone

0B0C8C4

Species Reactivity

Human

Immunogen

Recombinant protein corresponding to human FABP2.

Conjugate

Application Notes

ELISA (1:10000); WB (1:500-1:2000); Immunohistochemistry (1:200-1:1000); Immunofluorescence (1:200-1:1000); Flow Cytometry (1:200-1:400) & The optimal working dilution should be determined by the end user.

Alternative Names

FABP2; fatty acid binding protein 2, intestinal; fatty acid-binding protein, intestinal; I FABP; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein; FABPI; I-FABP; MGC133132;

Entrez Gene ID

UniProt ID

Antigen Description

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.

Pathway

Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem;