Mouse Anti-Human F9 Light Chain Monoclonal antibody, clone 24G53-G7

Antibody Isotype

IgG1

Clone

24G53-G7

Species Reactivity

Human; Rat; Pig; Bovine

Immunogen

human FIX

Conjugate

Application Notes

ELISA, IB
ELISA: Binds immobilized human, rat, porcine, and bovine FIX and human FIXa.
Immunoblotting: Binds human FIX and light chain of human FIXa under reduced conditions.
Inhibition: Does not prolong plasma clot time in aPTT clotting assay.
Recommended working dilution: Approximately 1-5 μg/ml. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded

Alternative Names

F9; coagulation factor IX; Christmas disease; Factor IX; FIX; hemophilia B; plasma thromboplastic component; F9 p22; FIX F9; factor 9; factor IX F9; serine protease; Christmas factor; plasma thromboplastin component; P19; PTC; HEMB; THPH8; MGC129641; MGC1

Entrez Gene ID

UniProt ID

Antigen Description

Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.

Pathway

Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Extrinsic Pathway, organism-specific biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Gamma-carboxylation of protein precursors, organism-specific biosystem;