Full length protein corresponding to Human Ext1 aa 1-746.Sequence: MQAKKRYFILLSAGSCLALLFYFGGLQFRASRSHSRREEHSGRNGLHHPS PDHFWPRFPDALRPFVPWDQLENEDSSVHISPRQKRDANSSIYKGKKCRM ESCFDFTLCKKNGFKVYVYPQQKGEKIAESYQNILAAIEGSRFYTSDPSQ ACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWN
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
EXT1; exostosin 1; exostoses (multiple) 1; Langer Giedion syndrome chromosome region; LGCR, LGS; exostosin-1; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltran
Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor.
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