Anti-Estrone monoclonal antibody (DMAB31893)

Mouse anti-Human IL8 monoclonal antibody for IA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG
Clone
N504
Species Reactivity
N/A
Immunogen
Estrone-BSA
Conjugate
Unconjugated

Target


Alternative Names
Estrone antibody; Mouse Anti-Estrone Monoclonal Antibody; Anti-Estrone Monoclonal Antibody; Estrone Monoclonal Antibody; Mouse Anti-Estrone MAb; Anti-Estrone MAb

Product Background


Antigen Description
Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is produced primarily from androstenedione originating from the gonads or the adrenal cortex. In premenopausal women, more than 50% of the estrone is secreted by the ovaries. In prepubertal children, men and non supplemented postmenopausal women the major portion of estrone is derived from peripheral tissue conversion of androstenedione. Interconversion of estrone and estradiol also occurs in peripheral tissue. Bioassay data indicate that the estrogenic action is much less than estradiol. Estrone is a primary estrogenic component of several pharmaceutical preparations, including those containing conjugated and esterified estrogens. In premenopausal women estrone levels generally parallel those of estradiol. After menopause estrone levels increase, possibly due to increased conversion of androstenedione to estrone.

Citations


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References


Paschoal, PO; Campos, SMN; et al. Food allergy/hypersensitivity: Antigenicity or timing?. IMMUNOBIOLOGY 214:269-278(2009).
Lin, GJ; Deng, MC; et al. Yeast expressed classical swine fever E2 subunit vaccine candidate provides complete protection against lethal challenge infection and prevents horizontal virus transmission. VACCINE 30:2336-2341(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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