Anti-E. coli K99 Pilus Monoclonal antibody (DMAB6175)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
N2110125
Species Reactivity
E. coli
Immunogen
Escherichia coli K99 pilus antigen
Conjugate
Unconjugated

Target


Alternative Names
E.coli K99 protein; Escherichia coli K99 pilus; FANC; K99 fimbrial protein; K99 pilus; Enterobacteriaceae

Product Background


Antigen Description
K99 pilus antigen is frequently associated with enterotoxigenic strains of E. coli isolated from the intestine of calves, sheep and pigs. Pilus antigens have been shown to be the main attachment mechanism whereby EPEC attach to and colonize the small intestine of neonatal animals. Any mechanism which will interfere with this attachment and colonization process is capable of reducing the intestinal colonization, diarrhoea and mortality associated with K99 EPEC infections.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


WESTERMAN, RB; FORTNER, GW; et al. USE OF MONOCLONAL-ANTIBODIES SPECIFIC FOR THE (A)OVER-BAR DETERMINANT OF K88 PILI FOR DETECTION OF ENTEROTOXIGENIC ESCHERICHIA-COLI IN PIGS. JOURNAL OF CLINICAL MICROBIOLOGY 31:311-314(1993).
Varshney, BC; Ponnanna, NM; et al. Development of a monoclonal antibody-based co-agglutination test to detect enterotoxigenic Escherichia coli isolated from diarrheic neonatal calves. JOURNAL OF VETERINARY SCIENCE 8:57-64(2007).

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