Anti-EBV Glycoprotein E Monoclonal antibody (DMABT-51230ME)

Mouse Anti-EBV Glycoprotein E Monoclonal antibody for IHC, ELISA, FC, IF, IP, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
332
Species Reactivity
EBV
Immunogen
Epstein-Barr virus
Conjugate
Unconjugated

Target


Alternative Names
Latent membrane protein 1; EBV; Epstein Barr virus; HHV4; Human Herpesvirus 4; LMP1

Product Background


Antigen Description
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a virus of the herpes family, which includes herpes simplex virus 1 and 2, and is one of the most common viruses in humans. It is best known as the cause of infectious mononucleosis. It is also associated with particular forms of cancer, particularly Hodgkins lymphoma, Burkitts lymphoma, nasopharyngeal carcinoma, and central nervous system lymphomas associated with HIV. Finally, there is evidence that infection with the virus is associated with a higher risk of certain autoimmune diseases, especially dermatomyositis, systemic lupus erythematosus, rheumatoid arthritis, Sj?grens syndrome, and multiple sclerosis. LMP-1 is a six-span transmembrane protein that is also essential for EBV-mediated growth transformation. LMP-1 mediates signaling through the Tumor necrosis factor-alpha/CD40 pathway.

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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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