Anti-E. cloacae Monoclonal antibody (DMABT-51224ME)

Mouse Anti-E. cloacae Monoclonal antibody for ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
72/323
Species Reactivity
E. cloacae
Immunogen
Enterobacter cloacae NCTC 10005
Conjugate
Unconjugated

Target


Alternative Names
Picornavirales; Picornaviridae; Enterovirus; Enterovirus 71; EV71

Product Background


Antigen Description
Enteroviruses are a genus of (+)ssRNA viruses associated with several human and mammalian diseases. Serologic studies have distinguished 66 human enterovirus serotypes on the basis of antibody neutralization tests. Additional antigenic variants have been defined within several of the serotypes on the basis of reduced or nonreciprocal cross-neutralization between variant strains. On the basis of their pathogenesis in humans and animals, the enteroviruses were originally classified into four groups, polioviruses, Coxsackie A viruses (CA), Coxsackie B viruses (CB), and echoviruses, but it was quickly realized that there were significant overlaps in the biological properties of viruses in the different groups. Enteroviruses isolated more recently are named with a system of consecutive numbers: EV68, EV69, EV70, and EV71, etc. Enteroviruses affect millions of people worldwide each year, and are often found in the respiratory secretions (e. g. , saliva, sputum, or nasal mucus) and stool of an infected person. Historically, poliomyelitis was the most significant disease caused by an enterovirus, Poliovirus. There are 62 non-polio enteroviruses that can cause disease in humans: 23 Coxsackie A viruses, 6 Coxsackie B viruses,39echoviruses, and 5 other enteroviruses. Poliovirus, as well as coxsackie and echovirus are spread through the fecal-oral route. Infection can result in a wide variety of symptoms ranging from mild respiratory illness (common cold), hand, foot and mouth disease, acute hemorrhagic conjunctivitis, aseptic meningitis, myocarditis, severe neonatal sepsis-like disease, and acute flaccid paralysis.

Citations


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References


PADHYE, NV; DOYLE, MP; et al. PRODUCTION AND CHARACTERIZATION OF A MONOCLONAL-ANTIBODY SPECIFIC FOR ENTEROHEMORRHAGIC ESCHERICHIA-COLI OF SEROTYPES O157-H7 AND O26-H11. JOURNAL OF CLINICAL MICROBIOLOGY 29:99-103(1991).
ANLEZARK, GM; MELTON, RG; et al. THE BIOACTIVATION OF 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE (CB1954) .1. PURIFICATION AND PROPERTIES OF A NITROREDUCTASE ENZYME FROM ESCHERICHIA-COLI - A POTENTIAL ENZYME FOR ANTIBODY-DIRECTED ENZYME PRODRUG THERAPY (ADEPT). BIOCHEMICAL PHARMACOLOGY 44:2289-2295(1992).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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