Anti-EXTL2 monoclonal antibody, clone FQS22241

Antibody Isotype

IgG

Clone

FQS22241

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide, corresponding to residues in Human EXTL2 (UniProt: Q9UBQ6).

Conjugate

Application Notes

WB: 1/1000 - 1/5000; IHC-P: 1/50 - 1/100;

Alternative Names

EXTL2; exostoses (multiple)-like 2; exostosin-like 2; alpha 1; 4 N acteylhexosaminyltransferase; alpha-GalNAcT EXTL2; EXT-related protein 2; processed exostosin-like 2; alpha-1,4-N-acteylhexosaminyltransferase; alpha-1,4-N-acetylhexosaminyltransferase EXT

Entrez Gene ID

UniProt ID

Antigen Description

Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

Pathway

Glycosaminoglycan biosynthesis - heparan sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - heparan sulfate, conserved biosystem; Glycosaminoglycan biosynthesis, heparan sulfate backbone, organism-specific biosystem; Glycosaminoglycan biosynthesis, heparan sulfate backbone, conserved biosystem; Metabolic pathways, organism-specific biosystem; heparan sulfate biosynthesis, organism-specific biosystem; heparan sulfate biosynthesis, conserved biosystem;