EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3->5 exoribonuclease complex and is required for the 3 processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3-5 exonuclease activity.
Pathway
Activation of Genes by ATF4; Deadenylation-dependent mRNA decay; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1); Destabilization of mRNA by KSRP; Destabilization of mRNA by Tristetraprolin (TTP); Diabetes pathways; Disease
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
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Certificate of Analysis