Anti-EXOSC3 monoclonal antibody, clone FQS25951(C)

Name: Anti-EXOSC3 monoclonal antibody, clone FQS25951(C)
SKU: DCABH-7943

Rabbit anti-Human EXOSC3 monoclonal antibody for WB, IHC-P, FC, IP, ICC/IF

COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Clone

FQS25951(C)

Species Reactivity

Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human EXOSC3 aa 1-100 (N terminal). The exact sequence is proprietary.Database link: Q9NQT5

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/10000 - 1/50000; IHC-P: 1/50; Flow Cyt: 1/100; IP: 1/50 - 1/70; ICC/IF: 1/100;

Target

Alternative Names

EXOSC3; exosome component 3; exosome complex component RRP40; CGI 102; CGI 102 protein; exosome component Rrp40; hRrp 40; hRrp40p; p10; RRP40; Rrp40p; exosome complex exonuclease RRP40; ribosomal RNA-processing protein 40; CGI-102; hRrp-40; bA3J10.7; MGC7

Entrez Gene ID

51010

UniProt ID

Q9NQT5

Product Background

Antigen Description

EXOSC3 is a component of the exosome 3->5 exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3 untranslated regions. It is required for the 3processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3-5 exonuclease activity. [Swiss-Prot]

Pathway

Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;

Citations