Anti-EXOG monoclonal antibody (DMABT-H16281)

Mouse anti-Human EXOG monoclonal antibody for ELISA Datasheet

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Host Species
Antibody Isotype
Species Reactivity
ENDOGL1 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.


Alternative Names
EXOG; endo/exonuclease (5-3), endonuclease G-like; ENDOGL1, ENDOGL2, endonuclease G like2, endonuclease G like 2; nuclease EXOG, mitochondrial; ENGL; ENGL a
Entrez Gene ID
UniProt ID

Product Background

Gene summary
EXOG (Endo/Exonuclease (5-3), Endonuclease G-Like) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and endonuclease activity. An important paralog of this gene is ENDOG. This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
Antigen Description
Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5-3 exonuclease activity. The function about EXOG antigen include endonuclease activity; hydrolase activity; metal ion binding; nucleic acid binding.


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Duguay, BA; Smiley, JR; et al. Mitochondrial Nucleases ENDOG and EXOG Participate in Mitochondrial DNA Depletion Initiated by Herpes Simplex Virus 1 UL12.5. JOURNAL OF VIROLOGY 87:11787-11797(2013).
Kieper, J; Lauber, C; et al. Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans. PROTEIN EXPRESSION AND PURIFICATION 73:99-106(2010).

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