Anti-EXOG monoclonal antibody (DMABT-H16281)

Mouse anti-Human EXOG monoclonal antibody for ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3G8
Species Reactivity
Human
Immunogen
ENDOGL1 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
EXOG; endo/exonuclease (5-3), endonuclease G-like; ENDOGL1, ENDOGL2, endonuclease G like2, endonuclease G like 2; nuclease EXOG, mitochondrial; ENGL; ENGL a
Entrez Gene ID
UniProt ID

Product Background


Gene summary
EXOG (Endo/Exonuclease (5-3), Endonuclease G-Like) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and endonuclease activity. An important paralog of this gene is ENDOG. This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
Antigen Description
Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5-3 exonuclease activity. The function about EXOG antigen include endonuclease activity; hydrolase activity; metal ion binding; nucleic acid binding.

Citations


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References


EKBLOM, A; SEGERDAHL, M; et al. ADENOSINE INCREASES THE CUTANEOUS HEAT PAIN THRESHOLD IN HEALTHY-VOLUNTEERS. ACTA ANAESTHESIOLOGICA SCANDINAVICA 39:717-722(1995).
Scibior, A; Zaporowska, H; et al. Lipid peroxidation in the kidney of rats treated with V and/or Mg in drinking water. JOURNAL OF APPLIED TOXICOLOGY 30:487-496(2010).

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