ESM1 (NP_008967, 85 a.a. ~ 184 a.a) partial recombinant protein with GST tag. The sequence is PSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVTKSSN RFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWLNPR
This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.
Pathway
Gastric cancer network 1;
Citations
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