ERCC3 (AAH08820, 29 a.a. ~ 128 a.a) partial recombinant protein with GST tag. The sequence is APGNDPQEAVPSAAGKQVDESGTKVDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEA FSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVS
Conjugate
Unconjugated
Target
Alternative Names
ERCC3; excision repair cross-complementation group 3; XPB; BTF2; GTF2H; RAD25; TFIIH; TFIIH basal transcription factor complex helicase XPB subunit; BTF2 p89; TFIIH p89; TFIIH 89 kDa subunit; DNA excision repair protein ERCC-3; DNA repair protein compleme
ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.
Pathway
Basal transcription factors; DNA Repair; Dual incision reaction in GG-NER; Epigenetic regulation of gene expression
Citations
Publication ()
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