ERBB2IP (NP_061165, 1272 a.a. ~ 1371 a.a) partial recombinant protein with GST tag. The sequence is QGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPG DKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVREVSS
Conjugate
Unconjugated
Target
Alternative Names
ERBB2IP; erbb2 interacting protein; LAP2; ERBIN; HEL-S-78; protein LAP2; densin-180-like protein; epididymis secretory protein Li 78;
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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