Flow Cytometry (0.5-1 ug/million cells); Immunofluorescence (1-2 μg/mL); Immunohistochemistry (1-2 μg/mL for 30 min at RT); Immunoprecipitation (1-2 ug/500 ug protein); WB (0.25-0.5 μg/mL) & The optimal working dilution should be determined by the end user
Target
Alternative Names
EPCAM; epithelial cell adhesion molecule; antigen identified by monoclonal AUA1 , M4S1, MIC18, TACSTD1, tumor associated calcium signal transducer 1; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99;
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Citations
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Q: I would like to know what the buffer formulation of Anti-EPCAM monoclonal antibody, clone 434/B4 is, please.
A: Yes, the buffer formulation for Anti-EPCAM monoclonal antibody, clone 434/B4 is supplied in In PBS, pH 7.4 (0.05% BSA, 0.05% sodium azide).
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