Anti-EPAS1 polyclonal antibody (DPABH-26010)

Rabbit anti-Human EPAS1 (aa 350-450) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to Human HIF-2-alpha aa 350-450 conjugated to Keyhole Limpet Haemocyanin (KLH).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1μg/ml; IHC-P: 1μg/ml; ICC/IF: 10μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EPAS1; endothelial PAS domain protein 1; HLF; MOP2; ECYT4; HIF2A
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adipogenesis; Cellular responses to stress; HIF-2-alpha transcription factor network; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha

Citations


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References


Ryu, JH; Yang, S; et al. Interleukin-6 Plays an Essential Role in Hypoxia-Inducible Factor 2 alpha-Induced Experimental Osteoarthritic Cartilage Destruction in Mice. ARTHRITIS AND RHEUMATISM 63:2732-2743(2011).
Wada, T; Shimba, S; et al. Transcriptional regulation of the hypoxia inducible factor-2 alpha (HIF-2 alpha) gene during adipose differentiation in 3T3-L1 cells. BIOLOGICAL & PHARMACEUTICAL BULLETIN 29:49-54(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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