The ENTPD7 belongs to the GDA1/CD39 NTPase family and the gene resides on chromosome 10q23-q24 and contains 12 exons and 11 introns covering a genomic region of approximately 46 kilobase pairs. The subcellular localization and enzymatic activity of ENTPD7 indicated that ENTPD7 is indeed an endo-apyrase with substrate preference for nucleoside triphosphates UTP, GTP, and CTP.
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