Specifications
Immunogen
Synthetic peptide corresponding to residues in Human EIF4EL3 (UniProt: O60573)
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100; ICC/IF: 1/100 - 1/250; IP: 1/10 - 1/100;
Target
Alternative Names
EIF4E2; eukaryotic translation initiation factor 4E family member 2; EIF4EL3, eukaryotic translation initiation factor 4E like 3; eukaryotic translation initiation factor 4E type 2; 4EHP; IF4e; eIF4E type 2; eIF-4E type 2; eIF4E-like protein 4E-LP; mRNA
Product Background
Antigen Description
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Pathway
Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; ISG15 antiviral mechanism, organism-specific biosystem; Immune System, organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem; Interferon Signaling, organism-specific biosystem;
Citations
Publication ()
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COA
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