Anti-eIF2S1 monoclonal antibody (DCABH-434)

Mouse anti-Human eIF2S1 monoclonal antibody for WB, FC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4I8
Species Reactivity
Rat, Dog, Human, Monkey
Immunogen
Recombinant full length Human EIF2S1 produced in HEK293T cells (NP_004085).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/2000; Flow Cyt: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; EIF2, eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ); eukaryotic translation initiation factor 2 subunit 1; EIF 2alpha; EIF2A
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem;

Citations


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References


Dey, S; Tameire, F; et al. PERK-ing up autophagy during MYC-induced tumorigenesis. AUTOPHAGY 9:612-614(2013).
Niso-Santano, M; Shen, S; et al. Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy. AUTOPHAGY 9:415-417(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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