EIF2B5 (NP_003898, 622 a.a. ~ 720 a.a) partial recombinant protein with GST tag. The sequence is LPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETI LSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
Pathway
Cap-dependent Translation Initiation; Gene Expression; MicroRNAs in cardiomyocyte hypertrophy; RNA transport
Citations
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Q: What experiments can DPAB-DC3682 antibodies be used for?
A: WB, ELISA
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