Anti-eIF2A monoclonal antibody (DCABH-7296) Knockout Validated

Mouse anti-Human eIF2A monoclonal antibody for FC, IHC-P, WB

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4B8C22
Species Reactivity
Mouse, Rat, Human, Monkey
Immunogen
Recombinant fragment corresponding to Human eIF2A aa 448-576. (Expressed in E.coli).Sequence: PPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEAKKAA KQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNLKKKLKAI EQLKEQAATGKQLEKNQLEK IQKETALLQ Database link: Q9BY44
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 1/200 - 1/400; IHC-P: 1/200 - 1/1000; WB: 1/500 - 1/2000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EIF2A; eukaryotic translation initiation factor 2A, 65kDa; eukaryotic translation initiation factor 2A; EIF 2A; 65 kDa eukaryotic translation initiation factor 2A; CDA02
Entrez Gene ID
UniProt ID

Product Background


Pathway
IL-6 Signaling Pathway, organism-specific biosystem; TGF-beta receptor signaling, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Pakay, JL; Hobbs, AA; et al. The role of eukaryotic initiation factor 2 alpha during the metabolic depression associated with estivation. JOURNAL OF EXPERIMENTAL BIOLOGY 206:2363-2371(2003).
Sawitzki, B; Kieselbach, B; et al. IFN-gamma regulation in anti-CD4 antibody-induced T cell unresponsiveness. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 15:695-703(2004).

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