Anti-PUf68 monoclonal antibody (DMAB9183MD)

Mouse anti-drosophila PUf68 monoclonal antibody for WB, IHC, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
6G10-12
Species Reactivity
drosophila
Immunogen
Drosophila protein expressed in E. coli
Conjugate
Unconjugated

Target


Alternative Names
pUf68; poly U binding factor 68kD; anon-WO0118547.408; CG12085; dFIR; Dmel\CG12085
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
The gene poly U binding factor 68kD is referred to in FlyBase by the symbol Dmel\pUf68 (CG12085, FBgn0028577). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: nuclear mRNA splicing, via spliceosome; cystoblast division; mRNA splice site selection; regulation of cell growth; alternative nuclear mRNA splicing, via spliceosome; regulation of cell cycle; regulation of alternative nuclear mRNA splicing, via spliceosome; neurogenesis. The function about PUf68 antigen include mRNA binding; nucleotide binding; poly(U) RNA binding; protein binding.
Pathway
Spliceosome.

Citations


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References


Wang, SZ; Wagner, EJ; et al. Half Pint/Puf68 is required for negative regulation of splicing by the SR factor Transformer2. RNA BIOLOGY 10:1396-1406(2013).
Mitchell, NC; Johanson, TM; et al. Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner. DEVELOPMENT 137:2875-2884(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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